2014

J. Song, Y. Tamura, T. Yoshihisa, and T. Endo

A novel import route for an N-anchor mitochondrial outer membrane protein aided by the TIM23 complex

EMBO Rep. in press (2014)

500. D.Maruyama, T. Sugiyama, T. Endo, and S. Nishikawa
     

Multiple BiP gens of Alabidopsis thaliana are required for male gametogenesis and pollen competitiveness

Plant Cell Physiol. in press (2014)

8. H.Okamoto, A. Miyagawa, T. Shiota, Y. Tamura, and T. Endo
   

Intra-molecular disulfide bond of Tim22 maintains integrity of the TIM22 complex in the mitochondrial inner membrane

10. J.Biol. Chem. 289, 4827-4838 (2014)
    

2. B.Rahman, S. Kawano, K. Yunoki-Esaki, T. Anzai, and T. Endo
   

NMR analyses on the interactions of the yeast Tim50 C-terminal region with the presequence and Tim50 core domain

FEBS Lett. 588, 678-684 (2014)

2013

T. Shiota, S. Nishikawa, and T. Endo

Analyses of protein-protein interactions by in vivo photocrosslinking in budding yeast

in Meth. Mol. Biol. "Membrane Biogenesis" (eds. D. Rapaport and J. M. Herrmann）, pp207-217，Springer (2013)

Y. Tamura, Y. Harada, S. Nishikawa, K. Yamano, M. Kamiya, T. Shiota, T. Kuroda, O. Kuge, H. Sesaki, K. Imai, K. Tomii, and T. Endo

Tam41 is a CDP-diacylglycerol synthase required for cardiolipin biosynthesis in mitochondria

Cell Metab. 17, 709-718 (2013)

Y. Tamura and T. Endo

Unveiling the last missing link of the cardiolipin synthetic pathway in mitochondria (Editorial)

Aging 6, 392-393 (2013)

遠藤斗志也

（私のメンター）Gottfried Schatz　ミトコンドリア生合成研究の先駆者

実験医学 31, 937-942 (2013)

2012

25. Y.Tamura, O. Onguka, K. Itoh, T. Endo, M. Iijima, S. M. Claypool, H. Sesaki
    

Phosphatidylethanolamine biogenesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins, Ups1p and Ups2p.
J. Biol. Chem. 287, 43961-43971(2012)

20. T.Shiota*, M. Maruyama*, M. Miura*, Y. Tamura*, K. Yamano, M. Esaki, and T. Endo
    

(* These authors contributed equally to this work.)
The Tom40 assembly process probed using the attachment of different intra-mitochondrial sorting signals.
Mol. Biol. Cell 23,3936-3947 (2012)

20. T.Izawa, T. Tsuboi, K. Kuroha, T. Inada, S. Nishikawa, and T. Endo
    

Role of Dom34:Hbs1 in non-stop protein clearance for normal organelle protein influx
Cell Reports 2, 447-453 (2012)

塩田拓也，西川周一,　遠藤斗志也
(Close Up実験法)動的なタンパク質相互作用の「スナップショット」を撮る～in vivoにおける部位特異的光架橋法
実験医学30,　1799-1805(2012)

20. T.Izawa, H. Nagai, T. Endo, and S. Nishikawa
    

Yos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation
Mol. Biol. Cell 23, 1283-1293 (2012)

2011

T. Shiota, H. Mabuchi, S. Tanaka-Yamano, K. Yamano, and T. Endo
In vivo protein-interaction mapping of a mitochondrial translocator protein Tom22 at work
Proc. Natl. Acad. Sci. USA 108, 15179-15183 (2011)

S. Mori, T. Kajita, T. Endo, and T. Yoshihisa
The intron of tRNA-TrpCCA is dispensable for growth and translation of Saccharomyces cerevisiae.
RNA 17, 1760-1769 (2011)

T. Endo, K. Yamano, and S. Kawano
Structural insight into the mitochondrial protein import system
Biochim. Biophys. Acta (Biomembranes) 1808, 955-970 (2011)

S.C. Botelho, M. Osterberg, A.S. Reichert, K. Yamano, P. Bjorkholm, T. Endo, G. von Heijne, and H. Kim

TIM23-mediated insertion of transmembrane α-helices into the mitochondrial inner membrane

EMBO J. 30, 1003-1011 (2011)

8. H.Yamamoto, N. Itoh, S. Kawano, Y. Yatsukawa, T. Momose, T. Makio, M. Matsunaga, M. Yokota, M. Esaki, T. Shodai, D. Kohda, A.E.A Hobbs, R.E. Jensen, and T. Endo
   

Dual Role of the receptor Tom20 in specificity and efficiency of protein import into mitochondria

Proc. Natl Acad. Sci. USA 108, 91-96 (2011)

20. T.Endo, S. Kawano, and K. Yamano
    

BamE structure: insight into the assembly of β-barrel proteins in the outer membranes of bacteria and mitochondria

EMBO Rep. (Hot off the press) 12, 94-95 (2011)

2010

11. K.Yamano, S. Tanaka-Yamano, and T. Endo
    

Tom7 regulates Mdm10-mediated assembly of the mitochondrial import channel protein Tom40

J. Biol. Chem. 285, 41222-41231 (2010)

T. Mori, C. Ogasawara, T. Inada, M. Englert, H. Beier, M. Takezawa, T. Endo, and T. Yoshihisa
Dual functions of yeast tRNA ligase in the unfolded protein response: unconventional cytoplasmic splicing of HAC1 pre-mRNA is not sufficient to release translational attenuation
Mol. Biol. Cell 21, 3722-3734 (2010). (A Highlights from  MBoC Selection)

T. Endo, K. Yamano, and T. Yoshihisa
Mitochondrial matrix reloaded with RNA
Cell (Preview) 142, 362-363 (2010)

遠藤斗志也，山野晃史，原田佳宗，河野　慎
ミトコンドリアタンパク質の配送と機能化
実験医学 28, 2059-2064 (2010)

20. T.Endo, K. Yamano, and S. Kawano
    

Structural basis for the disulfide relay system in the mitochondrial intermembrane space
Antioxid. Redox Signal. 13, 1359-1373 (2010)

M. Ruprecht, T. Bionda, T. Sato, M.S. Sommer, T. Endo, and E. Echleiff
On the impact of precursor unfolding during protein import into chloroplasts
Mol. Plant 3, 499-508 (2010)

M. Yamamoto, M. Kawanabe, Y. Hayashi, T. Endo, and S. Nishikawa
A vacuolar carboxypeptidase mutant of Arabidopsis thaliana is degraded by the ERAD pathway independently of its N-glycan.
Biochem. Biophys. Res. Commun. 393, 384-389(2010)

K. Yagawa, K. Yamano, T. Oguro, M. Maeda, T. Sato, T. Momose, S. Kawano, and T. Endo
Structural basis for unfolding pathway-dependent stability of proteins: vectorial unfolding vs. global unfolding
Protein Science, 19, 693-702 (2010)

Y. Harada, Y. Tamura, and T. Endo
Identification of yeast Art5 as a multicopy suppressor for the mitochondrial translocator maintenance protein Tam41.
Biochem. Biophys. Res. Commun. 392, 228-233 (2010)

K. Yamano, S. Tanaka-Yamano, and T. Endo
Mdm10 as a dynamic constituent of the TOB/SAM complex directs coordinated assembly of Tom40.
EMBO Rep. 11, 187-193 (2010)　

D. Maruyama, T. Endo, and S. Nishikawa
Bip-mediated polar nuclei fusion is essential for the regulation of endosperm nuclei proliferation in Arabidopsis thaliana.
Proc. Natl. Acad. Sci. USA 107, 1684-1689 (2010)

T. Endo and K. Yamano
Transport of proteins across or into the mitochondrial outer membrane
Biochim. Biophys. Acta (Molecular Cell Research), 1803, 706-714 (2010)

2009

H. Yamamoto, K. Fukui, H. Takahashi, S. Kitamura, T. Shiota, K. Terao, M. Uchida, M. Esaki, S. Nishikawa, T. Yoshihisa, K. Yamano, and T. Endo
Roles of TOM70 in import of presequence-containing mitochondrial proteins
J. Biol. Chem. 284, 31635-31646 (2009)

遠藤斗志也，西川周一
第8章　タンパク質の一生：誕生から死まで
医学 のための細胞生物学（永田和宏，塩田浩平編）83-96，南山堂
（2009.8）

S. Kawano, K. Yamano, M. Naoe, T. Momose, K. Terao, S. Nishikawa, N. Watanabe, and T. Endo
Structural basis of yeast Tim40 as an oxidative translocator in the mitochondrial intermembrane space
Proc. Natl. Acad. Sci. USA 106,14403-14407(2009)

T. Endo and K. Yamano
Multiple pathways for mitochondrial protein traffic
Biol. Chem. 390, 723-730 (2009)

Y. Tamura, T. Endo, M. Iijima, and H.Sesaki
Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria
J. Cell Biol. 185, 1029-1045 (2009)

T. Endo
Control and alteration of protein traffic in the cell
in Systems Biology - The Challenge of Complexity
(eds. S. Nakanishi, R. Kageyama, and D. Watanabe) pp129-134, Elsevier Science, Amsterdam (2009)

M. Sakoh-Nakatogawa, S. Nishikawa, and T. Endo
Roles of protein disulfide isomerase-mediated disulfide bond formation of yeast Mnl1p in ER-associated degradation.
J. Biol. Chem. 284, 11815-11825 (2009)

Y. Tamura, Y. Harada, T. Shiota, K. Yamano, K. Watanabe, M. Yokota, H. Yamamoto, H. Sesaki, and T. Endo
Tim23-Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import.
J. Cell Biol. 184, 129-141 (2009)

T. Oguro, K. Yagawa, T. Momose, T. Sato, K. Yamano, and T. Endo
Structural stabilities of different regions of the titin I27 domain contribute differently to unfolding upon mitochondrial protein import.
J. Mol. Biol. 385. 811-819 (2009)

2008

S. Nishikawa, A. Hirata, and T. Endo
Nuclear inner membrane fusion facilitated by yeast Jem1p is required for spindle pole body fusion but not for the first mitotic nuclear division during yeast mating.
Genes Cells, 13, 1185-1195 (2008)

M. Yamamoto, D. Maruyama, T. Endo, and S. Nishikawa
Arabidopsis thaliana has a set of J proteins in the endoplasmic reticulum that are conserved from yeast to animals and plants.
Plant Cell Physiol. 49, 1547-1562 (2008)

K. Yamano, M. Kuroyanagi-Hasegawa, M. Esaki, M. Yokota, and T. Endo
Step size analyses of the mitochondrial Hsp70 import motor reveal the Brownian ratchet in operation
J. Biol. Chem. 283, 27325-27332 (2008)

T. Makio, S. Nishikawa, T. Nakayama, H. Nagai, and T. Endo
Identification and characterization of a Jem1p ortholog of Candida albicans: dissection of Jem1p functions in karyogamy and protein quality control in Saccharomyces cerevisiae.
Genes Cells, 13, 1015-1026 (2008)

遠藤斗志也
局在化シグナル
「キーワード：蛋白質の一生」蛋白質核酸酵 素2008年6月号増刊（遠藤斗志也，小椋光，永田和宏，森和俊，田口英樹，吉田賢右編） 925 (2008)

遠藤斗志也
ジヒドロ葉酸レダクターゼ
「キーワード：蛋白質の一生」蛋 白質核酸酵素2008年6月号増刊（遠藤斗志也，小椋光，永田和宏，森和俊，田口英樹，吉田賢右編） 941 (2008)

遠藤斗志也
トランスロコン
「キーワード：蛋白質の一生」蛋白質核酸酵 素2008年6月号増刊（遠藤斗志也，小椋光，永田和宏，森和俊，田口英樹，吉田賢右編） 976 (2008)

遠藤斗志也
パワーストロークモデルとブラウニアンラチェットモデル
「キー ワード：蛋白質の一生」蛋白質核酸酵素2008年6月号増刊（遠藤斗志也，小椋光，永田和宏，森和俊，田口英樹，吉田賢右編） 982 (2008)

遠藤斗志也
ブルーネイティブ電気泳動
「キーワード：蛋白質の一生」蛋 白質核酸酵素2008年6月号増刊（遠藤斗志也，小椋光，永田和宏，森和俊，田口英樹，吉田賢右編） 992 (2008)

遠藤斗志也
ミトコンドリア
「キーワード：蛋白質の一生」蛋白質核酸酵 素2008年6月号増刊（遠藤斗志也，小椋光，永田和宏，森和俊，田口英樹，吉田賢右編） 1008 (2008)

遠藤斗志也
両親媒性ヘリックス
「キーワード：蛋白質の一生」蛋白質核 酸酵素2008年6月号増刊（遠藤斗志也，小椋光，永田和宏，森和俊，田口英樹，吉田賢右編）1020 (2008)

遠藤斗志也
TIM複合体
「キーワード：蛋白質の一生」蛋白質核酸酵素 2008年6月号増刊（遠藤斗志也，小椋光，永田和宏，森和俊，田口英樹，吉田賢右編）1093 (2008)

遠藤斗志也
TOM複合体
「キーワード：蛋白質の一生」蛋白質核酸酵素 2008年6月号増刊（遠藤斗志也，小椋光，永田和宏，森和俊，田口英樹，吉田賢右編）1095 (2008)

遠藤斗志也
βバレル型膜蛋白質
「キーワード：蛋白質の一生」蛋白質核 酸酵素2008年6月号増刊（遠藤斗志也，小椋光，永田和宏，森和俊，田口英樹，吉田賢右編）1103 (2008)

遠藤斗志也
ミトコンドリアを舞台とするタンパク質の交通
生物物理　 48, 4-10 (2008)

K. Yamano*, Y. Yatsukawa*, M. Esaki, A. E. A Hobbs, R. E. Jensen, and T. Endo
Tom20 and Tom22 share the common signal recognition pathway in mitochondrial protein import.
J. Biol. Chem. 283, 3799-3807 (2008)
* These authors contributed equally to this paper.

2007

T. Saitoh, M. Igura, T. Obita, T. Ose, R. Kojima, K. Maenaka, T. Endo, and D. Kohda
Tom20 recognizes mitochondrial presequences through dynamic equilibrium among multiple bound states
EMBO J. 26, 4777-4787 (2007)

西川周一，遠藤斗志也
3.8 ミトコンドリア（第III章 真核生物としての細胞体制）
酵母のすべて：系統，細胞から分子まで（大隅良典，下田　親編）65-76，シ ュプリンガージャパン
（2007）

吉久　徹，遠藤斗志也
4.1　細胞の構造：概論
生物物理学ハンドブッ ク（石渡信一，桂勲，桐野豊，美宅成樹編）193-197，朝倉書店
（2007）

T. Momose, C. Ohshima, M. Maeda, T. Endo
Structural basis of functional cooperation of Tim15/Zim17 with yeast mitochondrial Hsp70.
EMBO Rep. 8, 664-670(2007)

T. Yoshihisa, C. Ohshima, K. Yunoki-Esaki, and T. Endo
Cytoplasmic splicing of tRNA in Saccharomyces cerevisiae
Genes Cells 12, 285-297 (2007)

遠藤斗志也，吉久　徹，森　和俊，田口英樹
研究の歴史：渾沌の前史から「タン パク質の一生」研究が開花するまで
タンパク質の一生：集中マスター（遠藤斗志也，森和俊，田口英樹編）12-23，羊土社
(2007)

遠藤斗志也，吉久　徹，森　和俊，田口英樹
ブレイクスルーとなった実験法を中 心に：そのとき「タンパク質の一生」研究の歴史が動いた
タンパク質の一生：集中マスター（遠藤斗志也，森和俊，田口英樹編）25-35，羊土社
(2007)

遠藤斗志也
ブローベル・コード:交通管制という問題
タンパク質の一 生：集中マスター（遠藤斗志也，森和俊，田口英樹編）58-66，羊土社
(2007)

遠藤斗志也
トランスロコンはどうやって組立てられるのか
タンパク質の 一生：集中マスター（遠藤斗志也，森和俊，田口英樹編）130，羊土社
(2007)

遠藤斗志也
私のチャレンジしたい化学の未解決問題：オルガネラ構造を自在に操 り自らの 手で細胞をつくりたい
化学62, 20-21 (2007)

2006

吉久　徹，高野　晃，遠藤斗志也
核内tRNAの生理的意義
蛋白質核酸 酵素増刊「細胞核の世界」51,　2232-2234(2006)

*Y. Tamura, *Y. Harada, K. Yamano, K. Watanabe, D. Ishikawa, C. Ohshima, S. Nishikawa, H. Yamamoto, and T. Endo
Identification of Tam41 maintaining integrity of the TIM23 protein translocator complex in mitochondria
J. Cell Biol. 174, 615-623(2006)
* These authors contributed equally to this paper.

2005

T. Sato, M. Esaki, J. M. Fernandez, and T. Endo
Comparison of the protein unfolding pathways between mitochondrial protein import and atomic force microscopy measurements
Proc. Natl. Acad. Sci. USA, 102, 17999-18004 (2005)

西川周一，遠藤斗志也
第11章(1) タンパク質の膜透過装置
タンパ ク質科学：構造，物性，機能，　485-494
後藤祐児，桑島邦博，谷澤克行，化学同人　（2005）

遠藤斗志也
生体膜：脂質と二分子膜
物質環境科学I「分子から機能性物 質・生体まで」，208-225
田隅三生，浜田嘉昭，放送大学教育振興会　（2005）

遠藤斗志也
生体膜：膜タンパク質と膜輸送
物質環境科学I「分子から機 能性物質・生体まで」，226-239
田隅三生，浜田嘉昭，放送大学教育振興会　（2005）

永田和宏，遠藤斗志也
「タンパク質社会学」とは何か
実験医学増刊23 「細胞内タンパク質の社会学」（永田和宏，遠藤斗志也編），2213-2214 (2005)

遠藤斗志也，永田和宏
概論：タンパク質の一生とタンパク質社会学
実験 医学増刊23「細胞内タンパク質の社会学」（永田和宏，遠藤斗志也編），2228-2233 (2005)

遠藤斗志也
概説：タンパク質の配送・搬入とタンパク質が通る孔
実験医 学増刊23「細胞内タンパク質の社会学」（永田和宏，遠藤斗志也編），2272-2275 (2005)

遠藤斗志也，山本　林
ミトコンドリアの外膜内膜の孔
実験医学増刊 23（永田和宏，遠藤斗志也編），2297-2301 (2005)

西川周一，遠藤斗志也
ミトコンドリアの膜透過装置
細胞工学 24,786-790　（2005）

A. Takano, T. Endo, and T. Yoshihisa
tRNA actively shuttles between the nucleus and cytosol in yeast.
Science 309, 140-142 (2005)

M. Igura, T. Ose, T. Obita, C. Sato, K. Maenaka, T. Endo, and D. Kohda
Crystallization and preliminary X-ray analysis of mitochondrial presequence receptor Tom20 in complexes with a presequence from ALDH
Acta Cryst Section F61, 514-517 (2005)

遠藤斗志也
ミトコンドリア内にタンパク質が取込まれる仕掛け
現代化学 2月号, 28-33（2005）

K. Yamano, D. Ishikawa, M. Esaki, and T. Endo
Phosphate carrier has an ability to be sorted to either the TIM22 pathway or TIM23 pathway for its import into yeast mitochondria.
J. Biol. Chem. 280, 10011-10017 (2005)

H. Yamamoto, T. Momose, Y. Yatsukawa, C. Ohshima, D. Ishikawa, T. Sato, Y. Tamura, Y. Ohwa and T. Endo
Identification of a novel member of yeast mitochondrial Hsp70-associated motor and chaperone proteins that facilitates protein translocation across the inner membrane.
FEBS Lett. 579, 507-511 (2005)

2004

T. Endo
Protein transport to and within plant chloroplasts
Endocytobiosis Cell Res. 15, 294-299 (2004)

K. Nakatsukasa, S. Okada, K. Umebayashi, R. Fukuda, S. Nishikawa, and T. Endo
Roles of O-mannosylation of aberrant proteins in reduction of the load for endoplasmic reticulum chaperones in yeast
J. Biol. Chem. 279, 49762-49772 (2004)

M. Naoe, Y. Ohwa, D. Ishikawa, C. Ohshima, S. Nishikawa, H. Yamamoto, and T. Endo
Identification of Tim40 that mediates protein sorting to the mitochondrial intermembrane space
J. Biol. Chem. 279, 47815-47821 (2004)

M. Esaki, H. Shimizu, T. Ono, H. Yamamoto, T. Kanamori, S. Nishikawa, and T. Endo
Mitochondrial protein import: Requirement of the presequence elements and TOM components for precursor binding to the TOM complex
J. Biol. Chem. 279, 45701-45707 (2004)

D. Ishikawa, H. Yamamoto, Y. Tamura, K. Moritoh, and T. Endo
Two novel proteins in the mitochondrial outer membrane mediate β-barrel protein assembly
J. Cell Biol. 166, 621-627 (2004)

西川周一，中務邦雄，遠藤斗志也
小胞体品質管理におけるシャペロンと糖鎖の役 割：何が異常で何を除去すべきか
蛋白質核酸酵素増刊「細胞における蛋白質の一生」49,　988-991 (2004)

遠藤斗志也，吉久　徹
総論　蛋白質の移動（真核生物）：細胞内の交通管制シス テムがはたらく仕組み
蛋白質核酸酵素増刊「細胞における蛋白質の一生」49,　877-888 (2004)

T. Asai, T. Takahashi, M. Esaki, S. Nishikawa, K. Ohtsuka, M. Nakai, and T. Endo
Re-investigation of the requirement of cytosolic ATP for mitochondrial protein import
J. Biol. Chem. 279, 19464-19470 (2004)

2003

M. Esaki, T. Kanamori, S. Nishikawa, I. Shin, P. G. Schultz, and T. Endo
Tom40 protein import channel binds to non-native proteins and prevents their aggregation
Nature Struct. Biol. 10, 988-994 (2003)

遠藤斗志也，江崎雅俊，山本　林，吉久　徹
ミトコンドリアをめぐるタンパク質 フラックス
実験医学増刊「細胞内輸送研究の最前線」 21, 1889-1895 (2003)

T. Yoshihisa, K. Esaki, C. Ohshima, N. Tanaka, and T. Endo
Possibility of cytoplasmic pre-tRNA splicing: the yeast tRNA splicing endonuclease mainly localizes on the mitochondria
Mol. Biol. Cell 14, 3266-3279 (2003)

遠藤斗志也
特集：細胞内タンパク質の運命と翻訳から分解までを監視・制御する 細胞内システム
序にかえて：細胞内タンパク質の運命
実験医学 21, 866-868 (2003)

山本　林・江崎雅俊・遠藤斗志也
ミトコンドリアトランスロケータの連係プ レー：タンパク質配送の迷宮　２つの膜で囲まれたミトコンドリアの問題
実験医学 21, 880-885 (2003)

T. Endo, H. Yamamoto, and M. Esaki
Functional cooperation and separation of translocators in protein import into mitochondria, the double-membrane bounded organelles. (Commentary Article)
J. Cell Science 116. 3259-67 (2003)

T. Obita, T. Muto, T. Endo and D. Kohda
Peptide library approach with a disulfide tether to refine the Tom20 recognition motif in mitochondrial presequences.
J. Mol. Biol. 328, 495-504 (2003)

S. Nishikawa, Y. Terazawa, T. Nakayama, A. Hirata, T. Makio and T. Endo
Nep98p is a component of the yeast spindle pole body and essential for nuclear division and fusion
J. Biol. Chem. 278, 9938-9943 (2003)

2002

H. Yamamoto, M. Esaki, T. Kanamori, Y. Tamura, S. Nishikawa, and T. Endo
Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes
Cell 111, 519-528 (2002)

T. Endo and D. Kohda
Functions of outer membrane receptors in mitochondrial protein import (Review article).
Biochim. Biophys. Acta 1592, 3-14 (2002)

T. Endo
Mitochondrial protein flux
in Genome Science - Towards a New paradigm?
(eds. H. Yoshikawa, N. Ogasawara, and N. Satoh) pp27-32, Elsevier Science, Amsterdam (2002)

吉久　徹・遠藤斗志也
葉緑体包膜およびチラコイド膜を介する物質輸送とその制 御
朝倉植物生理学講座 3：光合成, pp109-116
（佐藤公行編）, 朝倉書店 (2002)

遠藤斗志也
オルガネラ形成と分子シャペロン　-　細胞が用意したタンパク質支 援システム
生物の科学　遺伝 14, 96-106 (2002)

遠藤斗志也・小代俊浩・江崎雅俊
ミトコンドリアへのタンパク質移行：難問/論 争にいかに決着をつけたか
実験医学 20, 7, 980-986 (2002)

河合明美・西川周一・遠藤斗志也
ミトコンドリアの形態学
ミトコンドリ アとミトコンドリア病
日本臨床 60, 増刊号4, 9-13 (2002)

2001

A. Kawai, S. Nishikawa, A. Hirata, and T. Endo
Loss of the mitochondrial Hsp70 functions causes aggregation of mitochondria in yeast cells.
J. Cell Sci. 114, 3565-3574 (2001)

S. Nishikawa, S. W. Fewell, Y. Kato, J. L. Brodsky, and T. Endo
Molecular chaperones in the yeast ER maintain the solubility of proteins for retro-translocation and degradation.
J. Cell Biol. 153, 1061-1070 (2001)

K. Nakatsukasa, S. Nishikawa, N. Hosokawa, K. Nagata, and T. Endo
Mnl1p, an α-mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins.
J. Biol. Chem. 276, 8635-8638 (2001)

T. Muto, T. Obita, Y. Abe, T. Shodai, T. Endo, and D. Kohda
NMR identification of the Tom20 binding segment in mitochondrial presequences.
J. Mol. Biol. 306, 137-143 (2001)

西川　周一・遠藤斗志也
輸送：小胞体
分子シャペロンによる細胞機能制 御, pp66-74
（永田和宏・森正敬・吉田賢右編）, シュプリンガー・フェアラーク東京 (2001)

2000

吉久　徹・遠藤斗志也
葉緑体の蛋白質輸送
蛋白質核酸酵素 45, 139-146 (2000)

Y. Abe, T. Shodai, T. Muto, K. Mihara, H. Torii, S. Nishikawa, T. Endo, and D. Kohda
Structural basis of presequence recognition by the mitochondrial protein receptor Tom20
Cell 100, 551-560 (2000)

K. Saeki, H. Suzuki, M. Tsuneoka, M. Maeda, R. Iwamoto, H. Hasuwa, S. Shida, T. Takahashi, M. Sakaguchi, T. Endo, Y Miura, E. Mekada, and K. Mihara
Identification of mammalian TOM22 as a subunit of the preprotein translocase of the mitochondrial outer membrane.
J. Biol. Chem. 275, 31996-32002 (2000)

遠藤斗志也
プロテイントラフィックの第一歩　-　生まれたタンパク質は，どこ に，どうやって行けばよいのか
タンパク質の一生：タンパク質の誕生，成熟から死まで（シリーズ　バイオサイエンスの新世紀2）, pp62-74
（中野明彦・遠藤斗志也編）, 共立出版 (2000)

1999

西川周一，遠藤斗志也

無細胞蛋白質生合成系：蛋白質生産システム

in: 生物化学実験法シリーズ：遺伝子発現研究法（江尻慎一郎，平　秀晴，堤　賢一，志村憲助編）pp257-264，学会出版センター (1999)

T. Kanamori, S. Nishikawa, M. Nakai, I. Shin, P. G. Schultz, and T. Endo

Uncoupling of transfer of the presequence and unfolding of the mature domain in precursor translocation across the mitochondrial outer membrane

Proc. Natl. Acad. Sci. USA 96, 3634-3639 (1999)

Y. Kubo, T. Tsunehiro, S. Nishikawa, M. Nakai, E. Ikeda, A. Toh-e. N. Morishima, T. Shibata, and T. Endo

Two distinct mechanisms operate in the reactivation of heat-denatured proteins by the mitochondrial Hsp70/Mdj1p/Yge1p chaperone system

J. Mol. Biol. 286, 447-464 (1999)

1000. M.Yoshida, T. Endo, K. Ito, N. Hosokawa, and K. Nagata
      

Dynamic and regulation of the stress response: meeting report on the stress response and molecular chaperones from Kyoto.

Cell Stress Chaperones 4, 66-74 (1999)

20. T.Asai, Y. Shinoda, T. Nohara, T. Yoshihisa, and T. Endo
    

Sec-dependent pathway and ΔpH-dependent pathway do not share a common translocation pore in thylakoidal protein transport

10. J.Biol. Chem. 274, 20075-20078 (1999)
    

1000. M.Esaki, T. Kanamori, S. Nishikawa, and T. Endo
      

Two distinct mechanisms drive protein translocation across the mitochondrial outer membrane in the late step of the cytochrome b2 import pathway.

Proc. Natl. Acad. Sci. USA 96, 11770-11775 (1999)

西川周一，遠藤斗志也

6.2.5　酵母の細胞内構造体の調製法

in: 新版　微生物学実験法 (大和田紘一，黒岩常祥，杉山純多，高橋秀夫，徳田　元，渡辺　信編.) pp121-125, 講談社サイエンティフィック 東京 (1999)

1998

T. Nohara, T. Yoshihisa, M. Nakai, and T. Endo

Cloning and characterization of chloroplast SecY proteins

in: Proceedings of the XIth International Congress on Photosynthesis (G. Gerab and J. Pusztai, eds.) pp3115-3118, Kluwer, Dordrecht (1998)

S. Nishikawa and T. Endo

Reinvestigation of the functions of the hydrophobic segment of Jem1p, a yeast endoplasmic reticulum membrane protein mediating nuclear fusion

Biochem. Biophys. Res. Commun. 244, 785-789 (1998)

M. Oka, M. Nakai, T. Endo, C. R. Lim, Y. Kimata and K. Khono

Loss of hsp70-hsp40 chaperone activity causes abnormal nuclear distribution and aberrant microtubule formation in M-phase of Saccharomyces cerevisiae

J. Biol. Chem. 273, 29737-29737 (1998)

西川周一，遠藤斗志也

オルガネラの機能解析：ミトコンドリア

in: 酵母ラボマニュアル-酵母分子細胞生物学実験法（山本正幸，大矢禎一編）pp191-211，シュプリンガーフェアラーク (1998)

野原哲矢，遠藤斗志也

in vitro転写・翻訳系を用いたタンパク質合成

細胞工学別冊 植物細胞工学シリーズ９：植物のタンパク質実験プロトコール：遺伝子と組織から迫るタンパク質の機能と構造 (中村研三，西村幹夫，長谷俊治，前島正義, eds.) pp 37-45 秀潤社 東京 (1998)

1997

T. Endo

Roles of molecular chaperones in mitochondrial protein import

in: Structure and functions of molecular chaperones: the roles of chaperones in the life cycle of proteins (A. Fink and Y. Goto, eds.) pp435-466, Marcell Decker (1997)

遠藤斗志也，浅井健好，金森　崇，西川周一

ミトコンドリアへのターゲティングと膜透過

細胞工学　16, 1275-1281 (1997)

J. Iwahashi, S. Yamazaki, T. Komiya, N. Nomura, S. Nishikawa, T. Endo, and K. Mihara

Analysis of the functional domain of the rat liver mitochondrial import receptor Tom20

J. Biol. Chem. 272, 18467-18472 (1997)

S. Nishikawa and T. Endo

The yeast JEM1p is a DnaJ-like protein of the endoplasmic reticulum membrane required for nuclear fusion

J. Biol. Chem. (Communication) 272, 12889-12982 (1997)

T. Kanamori, S. Nishikawa, I. Shin, P. G. Schultz, and T. Endo

Probing the environment along the protein import pathways in yeast mitochondria by site-specific photocrosslinking

Proc. Natl. Acad. Sci. USA 94, 485-490 (1997)

M. Sugita, H. Sugishita, T. Fujishiro, M. Tsuboi, C. Sugita, T. Endo, and M. Sugiura

Organization of a large gene cluster encoding ribosomal proteins in the cyanobacterium Synechococcus sp. strain PCC 6301: comparison of gene clusters among cyanobateria, eubacteria and chloroplast genomes

Genes 195, 73-79 (1997)

T. Endo

Assembly of thylakoid membrane proteins in chloroplasts

in: Membrane Protein: Structure, Function and Expression Control (N. Hamasaki and K. Mihara, eds.) 191-197, Kyushu University Press/ Karger Medical and Scientific Publishers (1997)

1996

T. Nohara, T. Asai, M. Nakai, M. Sugiura, and T. Endo

Cytochrome f encoded by the chloroplast genome is imported into thylakoids via the SecA-dependent pathway.

Biochem. Biophys. Res. Commun. 224, 474-478 (1996)

T. Endo, S. Mitsui, M. Nakai, and D. Roise

Binding of mitochondrial presequences to yeast cytosolic hsp70 depends on the amphiphilicity of the presequence.

J. Biol. Chem. 271, 4161-4167 (1996)

N. Pfanner, M. G. Douglas, T. Endo, N. J. Hoogenraad, R. E. Jensen, M. Meijer, W. Neupert, G. Schatz, U. K. Schmitz, and G. C. Shore

Uniform nomenclature for the protein transport machinery of the mitochondrial membranes.

Trends Biochem. Sci. 21, 51-52 (1996)

1995

T. Endo, T. Nohara, A. Goto, and M. Nakai

Roles of Sec proteins in protein transport within chloroplasts.

in: Research in Photosynthesis: from light to biosphere, vol. III (P. Mathis ed.) pp811-814, Kluwer, Amsterdam (1995)

M. Nakai, T. Nohara, D. Sugita, and T. Endo

Cloning and characterization of sec and ffh genes from the cyanobacterium Synechococcus PCC7942.

in: Research in Photosynthesis: from light to biosphere, vol. III (P. Mathis ed.) pp505-508, Kluwer, Amsterdam (1995)

M. Nakai and T. Endo

Identification of yeast MAS17 encoding the functional counterpart of the mitochondrial receptor complex protein MOM22 of Neurospora crassa.

FEBS Lett. 357, 202-206 (1995)

T. Endo, S. Mitsui and D. Roise

Mitochondrial presequences can induce aggregation of unfolded proteins.

FEBS Lett. 359, 93-96 (1995)

T. Nohara, M. Nakai, A. Goto, and T. Endo

Isolation and characterization of the cDNA for pea chloroplast SecA: evolutionary conservation of the bacterial-type SecA-dependent protein transport within chloroplasts.

FEBS Lett. 364, 305-308 (1995)

T. Endo, Y. Nakayama, and M. Nakai

Avidin fusion protein as a tool to generate a stable translocation intermediate spanning the mitochondrial membranes.

J. Biochem 118, 753-759 (1995)

M. Nakai, K. Kinoshita, and T. Endo

Mitochondrial receptor complex protein: the intermembrane-space domain of yeast MAS17 is not essential for its targeting or function.

J. Biol. Chem. 270, 30571-30575 (1995)

中井正人、西川周一、遠藤斗志也

分子シャペロンhsp70とオルガネラ形成

生化学 67, 108-122 (1995)

遠藤斗志也

フレッシュマンのための分野別化学研究の見方、考え方：生物化学分野

in vitroとin vivo実験の意味と限界を認識しよう

化学 50, 210-212 (1995)

遠藤斗志也

ミトコンドリアへの蛋白質輸送におけるストレス蛋白質の役割

生体の科学 46, 324-327 (1995)

1994

M. Nakai, Y. Kato, E. Ikeda, A. Toh-e and T. Endo

Yge1p, a eukaryotic GrpE homolog, is localized in the mitochondrial matrix and interacts with mitochondrial hsp70.

Biochem. Biophys. Res. Commun. 200, 435-442 (1994)

M. Nakai, T. Nohara, D. Sugita and T. Endo

Identification and characterization of the SecA protein homologue in the cyanobacterium Synechococcus PCC7942.

Biochem. Biophys. Res. Commun. 200, 844-851 (1994)

T. Endo, M. Kawakami, A. Goto, T. America, P. Weisbeek and M. Nakai

Chloroplast protein import: chloroplast envelopes and thylakoids have different abilities to unfold proteins.

Eur. J. Biochem. 225, 403-409 (1994)

M. Nakai, A. Goto, T. Nohara, D. Sugita, and T. Endo

Identification of the SecA protein homolog in pea chloroplasts and its possible involvement in thylakoidal protein transport.

J. Biol. Chem.(Communication) 269, 31338-31341 (1994)

遠藤斗志也

ミトコンドリア移行

Annual Review　細胞生物学 （矢原一郎、御子芝克彦、月田承一郎編）, 32-44， 中外医学社 (1994)

遠藤斗志也

1994年の化学：タンパク質の水素原子交換を引き起 こす「揺らぎ」の実体

化学 49, 302-303 (1994)

1993

M. Nakai, D. Sugita, T. Omata and T. Endo

SecY Protein is localized in both the cytoplasmic and thylakoid membranes in the cyanobacterium Synechococcus PCC7942.

Biochem. Biophys. Res. Commun. 193, 228-234 (1993)

M. Nakai, T. Takada and T. Endo

Cloning of the YAP19 gene encoding a putative yeast homolog of AP19, the mammalian small chain of the clathrin-assembly proteins.

Biochim. Biophys. Acta 1174, 282-284 (1993)

M. Nakai, T. Endo, T. Hase and H. Matsubara

Intramitochondrial protein sorting: isolation and characterization of the yeast MSP1 gene which belongs to a novel family of putative ATPases.

J. Biol. Chem. 268, 24262-24269 (1993)

M. Nakai, A. Takeda, M. L. Cleary and T. Endo

The Bcl-2 protein is inserted into the outer membrane but not into the inner membrane of rat liver mitochondria in vitro. Biochem. Biophys. Res. Commun. 196, 233-239 (1993)

M. Nakai, T. Endo, T. Hase, Y. Tanaka, B. L. Trumpower, H. Ishiwatari, A. Asada, M. Bogaki and H. Matsubara

Acidic regions of cytochrome c1 are essential for ubiquinol-cytochrome c reductase activity in yeast cells lacking the acidic QCR6 protein.

J. Biochem. 114, 919-925 (1993)

遠藤斗志也

1993年の化学：タンパク質のミトコンドリア内での 仕分け経路

化学 48, 68-69 (1993)

1992

T. Endo, K. Kawamura and M. Nakai

Chloroplast targeting domain of plastocyanin transit peptide can form a helical structure but does not have a high affinity for lipid bilayers.

Eur. J. Biochem. 207, 671-675 (1992)

M. Nakai, A. Tanaka, T. Omata and T. Endo

Cloning and characterization of the secY gene from the cyanobacterium Synechococcus PCC7942.

Biochim. Biophys. Acta 1171, 113-116 (1992)

T. Endo, K. Kawamura, H. Torii and M. Nakai

Conformation of the chloroplast-targeting domain of plastocyanin tarnsit peptide and its interaction with lipid bilayers.

in: Research in Photosynthesis Vol. III (ed. N. Murata), 181-184, Kluwer, Amsterdam (1992)

遠藤斗志也

DHFR融合タンパク質を用いたミトコンドリアタンパ ク質局在化機構の解析

新生化学実験講座６：生体膜と膜輸送（下）, 733-738, 東京化学同人, 東京 (1992)

1991

Y. Iizuka, T. Endo and M. Oya

Synthesis and properties of high molecular weight polypeptides containing of tryptophan.

Bull. Chem. Soc. Jpn. 64, 1336-1341 (1991)

T. Endo

Co-operative binding of hsp60 may promote transfer from hsp70 and correct folding of imported proteins in mitochondria.

FEBS Lett. 293, 1-3 (1991)

T. Endo and N. Tamiya

Structure-function relationship of postsynaptic neurotoxins from snake venoms.

in: International Encycropedia of Pharmacology and Therapeutics vol.134: Snake Toxins (ed. A. L. Harvey), 165-210, Pergamon, Oxford (1991)

遠藤斗志也

細胞内での蛋白質の折れたたみと局在化

蛋白質核酸酵素 36, 28-36 (1991)

遠藤斗志也

ミトコンドリアタンパク質の膜透過のメカニズム：前駆体の高次構造変化、膜電位の役割など

生物物理 31, 3-18 (1991)

遠藤斗志也、中井正人

ミトコンドリア膜透過実験法

蛋白質核酸酵素 36, 1951-1956 (1991)

遠藤斗志也

1991年の化学：タンパク質の膜透過チャネルの電気 生理学的な検出

化学 46, 651 (1991)

遠藤斗志也

アンチフォールディング、アンフォールディングによるタンパク質の機能化

高分子 40, 620-623 (1991)

1990

T. Endo and N. Tamiya

Postsynaptic neurotoxin: a flexible protein that binds to the acetylcholine receptor.

in: Protein Structural Analysis, Folding and Design (M. Hatano ed.), 37-52, Japan Scientific Society Press/Elsevier, Tokyo (1990)

遠藤斗志也

タンパク質の膜透過におけるリン脂質の役割

生化学 62, 113-117 (1990)

1989

M. Eilers, T. Endo and G. Schatz

Adriamycin, a drug interacting with acidic phospholipids, blocks import of precursor proteins by isolated mitochondria.

J. Biol. Chem. 264, 2945-2950 (1989)

T. Endo, M. Eilers and G. Schatz

Binding of a tightly folded artificial mitochondrial precursor protein to the mitochondrial outer membrane involves a lipid-mediated conformational change.

J. Biol. Chem. 264, 2951-2956 (1989)

T. Endo, M. Oya, K. Hayashi and T. Miyazawa

Step-wise thermal denaturation of cobrotoxin, a snake venom neurotoxin from Naja naja atra: a proton nuclear magnetic resonance study.

J. Protein Chem. 8, 575-581 (1989)

T. Endo, M. Oya, F. J. Joubert, K. Hayashi and T. Miyazawa

State of functionally essential Trp-29 in snake venom neurotoxins: a proton nuclear magnetic resonance study.

J. Protein Chem. 8, 583-588 (1989)

T. Endo and M. Oya

Conformational changes of a mitochondrial precursor protein on binding to phospholipid vesicles and sodium dodecyl sulfate micelles: a circular dichroism and fluorescence spectroscopy study.

FEBS Lett. 249, 173-177 (1989)

T. Endo, I. Shimada, D. Roise and F. Inagaki

N-terminal half of a mitochondrial presequence peptide takes a helical conformation when bound to dodecylphosphocholine micelles: a proton nuclear magnetic resonance study.

J. Biochem. 106, 396-400 (1989)

T. Endo, M. Oya, H. Ozawa, Y. Kawano, J. R. Giglio and T. Miyazawa

A proton nuclear magnetic resonance study on the solution structure of crotamine.

J. Protein Chem. 8, 807-815 (1989)

遠藤斗志也

蛋白質の膜透過におけるfolding/unfoldingの意義

実験医学 7, 164-167 (1989)

1988

T. Endo and G. Schatz

Latent membrane perturbation activity of a mitochondrial precursor protein is exposed by unfolding.

EMBO J. 7, 1153-1158 (1988)

T. Endo, M. Oya, R. Kaptein, G. W. Vuister, H. Kihara, N. Mohri, S. Tanaka and M. Ohno

Proton NMR resonance assignments and surface accessibility of tryptophan residues of a dimeric phospholipase A2 from Trimeresurus flavoviridis.

FEBS Lett. 230, 57-60 (1988)

M. Oya, T. Endo and Y. Iizuka

Solubility and conformation of high molecular weight synthetic copolypeptides in aprotic solvents. Dependence of phenyl pendant group on the solubility and conformation.

Polym. J. 20, 557-564 (1988)

1987

T. Endo, M. Oya, N. Tamiya and T. Miyazawa

Proton nuclear magnetic resonance characterization of phopholipase A2 from Laticauda semifasciata.

J. Biochem. 101, 795-804 (1987)

T. Endo, T. Ueda, H. Yamada and T. Imoto

 

pH Dependence of individual tryptophan N-1 hydrogen exchange rates in lysozyme and its chemically modified derivatives.

Biochemistry 26, 1838-1845 (1987)

T. Endo, M. Nakanishi, S. Furukawa, F. J. Joubert, N. Tamiya and K. Hayashi

Stopped-flow fluorescence studies on binding of snake neurotoxins to acetylcholine receptor.

J. Protein Chem. 6, 227-236 (1987)

T. Endo, M. Oya, N. Tamiya and K. Hayashi

Role of C-terminal tail of long neurotoxins from snake venoms in molecular conformation and acetylcholine receptor binding: proton nuclear magnetic resonance and competition binding studies.

Biochemistry 26, 4592-4598 (1987)

T. Endo and N. Tamiya

Current view on the structure-function relationship of postsynaptic neurotoxins from snake venoms.

Pharmacol. Ther. 34, 403-451 (1987)

1986

T. Endo, M. Nakanishi, S. Furukawa, F. J. Joubert, N. Tamiya and K. Hayashi

Stopped-flow fluorescence studies on binding kinetics of neurotoxins with acetylcholine receptor.

Biochemistry 25, 395-404 (1986)

T. Endo, H. S. Kim, N. Maeda, N. Tamiya and T. Miyazawa

Proton nuclear magnetic resonance analyses of the molecular conformations of unique long neurotoxins bearing Phe-25: Astrotia stokesii b, Astrotia stokesii c and Acanthophis antarcticus b.

J. Biochem. 99, 681-691 (1986)

K. Hayashi, T. Endo, M. Nakanishi, S. Furukawa, F. J. Joubert, Y. Inoue, H. Nomoto and N. Tamiya

On the mode of action of snake postsynaptic neurotoxins.

J. Toxicol. 5, 95-104 (1986)

遠藤斗志也、宮沢辰雄

NMRによる生体高分子のコンホメーション解析

化学総説：新しい磁気共鳴と化学への応用 49， 143-152， 日本化学会/学会出版センター， 東京 (1986)

1984

M. Shimamura, T. Endo, Y. Inoue, S. Inoue and H. Kambara

Fish egg polysialoglycoproteins: structures of new sialooligosaccharide chains isolated from the eggs of Oncorhynchus keta (Walbaum): fucose-containing units with oligosialyl groups.

Biochemistry 23, 317-322 (1984)

遠藤斗志也

タンパク質のNMR

化学の領域（増刊）NMR-総説と実験ガイド 142 （宮澤辰雄、荒田洋治編）, 95-118， 南江堂， 東京 (1984)

遠藤斗志也

NMRによるタンパク質のアミドプロトンの重水素交換 速度の測定

化学と工業 36, 664-665 (1984)

1983

M. Shimamura, T. Endo, Y. Inoue and S. Inoue

A novel neutral oligosaccharide chain found in polysialoglycoproteins isolated from pacific salmon eggs. Structural studies by secondary ion mass spectrometry, proton nuclear magnetic resonance spectroscopy, and chemical methods.

Biochemistry 22, 959-963 (1983)

T. Endo, I. Shimada, F. Inagaki and T. Miyazawa

Broensted relation for hydrogen-deuterium exchange reactions of imidazole-bearing molecules with amino groups.

Bull. Chem. Soc. Jpn. 56, 667-670 (1983)

T. Miyazawa, T. Endo, F. Inagaki, K. Hayashi and N. Tamiya

NMR analysis of structure and function of snake neurotoxins.

Biopolymers 22, 139-145 (1983)

1982

T. Endo, F. Inagaki, K. Hayashi and T. Miyazawa

Local conformational transition of toxin B from Naja naja as studied by nuclear magnetic resonance and circular dichroism.

Eur. J. Biochem. 122, 541-547 (1982)

R. C. Hider, A. F. Drake, F. Inagaki, R. J. P. Williams, T. Endo and T. Miyazawa

Molecular conformation of α-cobratoxin as studied by nuclear magnetic resonance and circular dichroism.

J. Mol. Biol. 158, 275-291 (1982)

H. Nomoto, T. Endo and Y. Inoue

Preparation and characterisation of fragment glycoasparagines from ovalbumin glycopeptides: reference compounds for structural and biochemical studies of the oligo-mannose and hybrid types of carbohydrate chains of glycoproteins.

Carbohydr. Res. 107, 91-101 (1982)

H. Nomoto, M. Iwasaki, T. Endo, S. Inoue, Y. Inoue and G. Matsumura

Structures of carbohydrate units isolated from trout egg polysialoglycoproteins: short-cored units with oligosialosyl groups.

Arch. Biochem. Biophys. 218, 335-341 (1982)

1981

T. Endo, F. Inagaki, K. Hayashi and T. Miyazawa

Proton-nuclear-magnetic-resonance study on molecular conformations of long neurotoxins α-bungarotoxin from Bungarus multicinctus and toxin B from Naja naja.

Eur. J. Biochem. 120, 117-124 (1981)

1979

T. Endo, F. Inagaki, K. Hayashi and T. Miyazawa

Conformation of cobrotoxin in aqueous solution as studied by nuclear magnetic resonance.

Eur. J. Biochem. 102, 417-430 (1979)